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*****ANNALES PHARMACEUTIQUES FRANCAISES*****
Lamaison JL  Petitjean-Freytet C  Carnat A  
[Rosmarinic acid, total hydroxycinnamic derivatives and antioxidant activity of
Apiaceae, Borraginaceae and Lamiceae medicinals]
Teneurs en acide rosmarinique, en derives hydroxycinnamiques totaux et activite
antioxydante chez les Apiacees, les Borraginacees et les Lamiacees medicinales.
In: Ann Pharm Fr (1990) 48(2):103-8
ISSN: 0003-4509  (Published in French)

A number of medicinal species of the Apiaceae, Borraginaceae and Lamiaceae
families present high rosmarinic acid and total hydroxycinnamic derivative
contents. Species of genera Sanicula (Apiaceae), Lycopus, Melissa, Mentha,
Origanum and Salvia (Lamiaceae) contain rosmarinic acid in large amount, more
than 3%, based on dry weight. The antioxidant activity of hydroalcoholic
extracts, on DPPH, is partly in relation with the hydroxycinnamic derivative
content.

Registry Numbers:
537-15-5 (rosmarinic acid)

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*****BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS*****
Turan K  Nagata K  Kuru A  
Antiviral effect of Sanicula europaea L. leaves extract on influenza
virus-infected cells.
In: Biochem Biophys Res Commun (1996 Aug 5) 225(1):22-6
ISSN: 0006-291X

We have investigated the influence of Sanicula europaea L. extracts on influenza
virus growth in MDCK cells. Fractions I, II, and III separated from Sanicula
extract with Sephadex column chromatography were found to be non-toxic against
MDCK cells. The growth of influenza A/PR/8/34 was completely inhibited by these
fractions, while that of influenza B/Lee/40 was not affected. Fractions II and
III have been shown not to have a direct virucidal activity on influenza
A/PR/8/34. Influenza A/Vic/1/75 produced microscopic plaques in the presence of
the extract. In vitro RNA synthesis with viral RNA-dependent RNA polymerase was
also inhibited by a water soluble extract of Sanicula. These observations
suggest that the Sanicula extract contains an anti-influenza virus substance.

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*****PHARMAZIE*****
Hiller K  
[On the contents of some saniculoids. 1. Sanicula europaea L.-- isolation and
quantitative understanding of chlorogenic and rosmarinus acid]
Zur Kenntnis der Inhaltsstoffe einiger Saniculoideae. 1. Sanicula europaea
L.--isolierung und quantitative Erfassung von Chlorogen- und Rosmarinsaure.
In: Pharmazie (1965 Sep) 20(9):574-9
ISSN: 0031-7144  (Published in German)

[No Abstract Available]

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